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What is Islet cell transplantation #bestcardiologistinperambur #bestangiodoctorperambur
Pancreatic islet cell transplantation is a procedure for type 1 Diabetes Mellitus to replace the decteoyed insulin producing beta cells with healthy , donor derived islet cells, usually infused into the liver to improve blood glucose control and reduce or eliminate the need for insulin injections. It is particularly effective for patients with severe hypoglycemic unawareness
Procedure Details
Source: Cells are isolated from a deceased donor pancreas.
Infusion: A catheter is inserted into the portal vein of the liver, and the islets are slowly infused, often guided by ultrasound or fluoroscopy.
Immunosuppression: Recipients take antirejection medications to prevent the immune system from attacking the new cells
Benefits
Improved Blood Sugar: Better, more stable glucose levels with fewer dangerous highs and lows.
Reduced Insulin Dependence: A significant percentage of patients become insulin-free, particularly within the first few years.
Hypoglycemia Awareness: Helps patients regain the ability to detect low blood sugar episodes
Risks & Limitations
Rejection: The immune system may still reject the cells.
Potential Complications: Nausea, fatigue, or potential bleeding/infection from the infusion procedure.
Long-term Efficacy: Some patients may need to restart insulin therapy as cell function can decrease over time
Key Applications
Type 1 Diabetes: Targeted at adults with unstable, "brittle" diabetes.
TPIAT: Total pancreatectomy with islet auto-transplant is used to prevent diabetes after removing the pancreas for chronic pancreatitis
Bus Stand, Dr Antony's Cardio Diabetic Centre, 7/158, 15th street, Jagannathan Salai, opposite to Periyar Nagar, Periyar Nagar West, Perambur, Chennai, Tamil Nadu 600082
600082
Chennai
India
08042781449
Dr Antony's Cardio Diabetic Centre
https://www.drantonyscardiodiabeticcentre.com
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