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What is Hypertrophic obstructive cardiomyopathy? #bestcardiologistinperambur

Hypertrophic Obstructive Cardiomyopathy (HOCM) is a genetic condition causing left ventricular hypertrophy .

HOCM is an important cause of sudden death in young individuals

Symptoms include shortness of breath, chest pain, dizziness, and fainting, particularly during exercise.

Treatment focuses on managing symptoms and preventing sudden cardiac death via medications (beta-blockers, CCBs), lifestyle changes, or procedures.

Key Aspects of HOCM:
  • Symptoms: Fatigue, shortness of breath, palpitations, dizziness, fainting, and chest pain (angina), often exacerbated by exertion.
  • Causes: Typically inherited (autosomal dominant) mutations in genes that code for heart muscle proteins (sarcomeric proteins).
  • Risk Factors: Family history of the condition or sudden unexplained death.
  • Prognosis: While many have a normal life expectancy, it is the leading cause of sudden cardiac death in young athletes (aged 10-35).
  • Treatment:
    • Medication: Beta-blockers, calcium channel blockers, or disopyramide to improve relaxation and reduce obstruction.
    • Procedures: Septal reduction therapy (surgical myectomy or alcohol septal ablation) to remove or shrink the thickened muscle.
    • Devices: Implantable cardioverter-defibrillators (ICD) to prevent sudden death.

 2026-03-14T04:12:04

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